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Gene Expression Data
Assay Details
Assay
Reference: J:85473 Corbin JG, et al., Combinatorial function of the homeodomain proteins Nkx2.1 and Gsh2 in ventral telencephalic patterning. Development. 2003 Oct;130(20):4895-906
Assay type: Immunohistochemistry
MGI Accession ID: MGI:2676238
Gene symbol: Gsx2
Gene name: GS homeobox 2
Antibody: GSH2 antibody
Detection system: Secondary antibody
Results
Specimen 1E,1F: embryonic day 10.0 (more )
Note: 27 somites. Triple labeled: blue - Gsx2; green - Pax6 (assay MGI:2676225); red - Nkx2-1 (assay MGI:2676233).
Structure Level Pattern Image Note
TS15: telencephalon Present Regionally restricted 1F , 1E Expressed laterally.

Specimen 1H,1I: embryonic day 10.5 (more )
Note: Triple labeled: blue - Gsx2; green - Pax6 (assay MGI:2676225); red - Nkx2-1 (assay MGI:2676233).
Structure Level Pattern Image Note
TS17: diencephalon Present Regionally restricted 1I , 1H Expressed in gap in expression of Pax6 and Nkx2.1 expands, partially overlapping with Pax6 expression, expanded more ventrally into Nkx2.1-positive domain.

Specimen 2A: embryonic day 10.5 (more )
Note: 36-38 somites. Double labeled: green - Gsx2; red - Nkx2-1 (assay MGI:2676233).
Structure Level Pattern Image Note
TS18: telencephalon Present Regionally restricted 2A In anterior telencephalon, expressed in lateral domain.

Specimen 2B: embryonic day 10.5 (more )
Note: 36-38 somites. Double labeled: green - Gsx2; red - Nkx2-1 (assay MGI:2676233).
Structure Level Pattern Image Note
TS18: telencephalon Present Regionally restricted 2B At the level of the septum, expression is non-overapping with Nkx2.1 expression.

Specimen 2C: embryonic day 10.5 (more )
Note: 36-38 somites. Double labeled: green - Gsx2; red - Nkx2-1 (assay MGI:2676233).
Structure Level Pattern Image Note
TS18: telencephalon Present Regionally restricted 2C More posteriorly, some Gsh2-positive cells observed within the Nkx2.1 domain.

Specimen 2D: embryonic day 10.5 (more )
Note: 36-38 somites. Double labeled: green - Gsx2; red - Nkx2-1 (assay MGI:2676233).
Structure Level Pattern Image Note
TS18: telencephalon Present Regionally restricted 2D More posteriorly, some Gsh2-positive cells observed within the Nkx2.1 domain.

Specimen 2E: embryonic day 10.5 (more )
Note: 36-38 somites. Double labeled: green - Gsx2; red - Nkx2-1 (assay MGI:2676233).
Structure Level Pattern Image Note
TS18: telencephalon Present Regionally restricted 2E More posteriorly, some Gsh2-positive cells observed within the Nkx2.1 domain.

Specimen 2F: embryonic day 10.5 (more )
Note: 36-38 somites. Double labeled: green - Gsx2; red - Nkx2-1 (assay MGI:2676233).
Structure Level Pattern Image Note
TS18: telencephalon Present Regionally restricted 2F At the most posterior level of telencephalon, highly expressed in the region of the presumptive caudal ganglionic eminence.

Specimen 3E: embryonic day 9.5 (more )
Note: 26-30 somites.
Structure Level Pattern Image Note
TS15: telencephalon Present Regionally restricted 3E

Specimen 3F: embryonic day 9.5; Nkx2-1tm1Shk/Nkx2-1tm1Shk (more )
Note: 26-30 somites.
Structure Level Pattern Image Note
TS15: telencephalon Present Regionally restricted 3F Expression in the lateral domain does not expand ventrally into the presumptive medial ganglionic eminence region.

Specimen Not shown: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: telencephalon Present Regionally restricted


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory