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Lrrc43 Gene Detail
Summary
  • Symbol
    Lrrc43
  • Name
    leucine rich repeat containing 43
  • Synonyms
    LOC381741
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685907
    NCBI Gene: 381741
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:123627368-123646268 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 63.01 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    552 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685907
 protein coding gene Chr5:123627349-123646268 (+)
129S1/SvImJ MGP_129S1SvImJ_G0030072
 protein coding gene Chr5:127228457-127247151 (+)
A/J MGP_AJ_G0030037
 protein coding gene Chr5:121952491-121972096 (+)
AKR/J MGP_AKRJ_G0029973
 protein coding gene Chr5:125890666-125911899 (+)
BALB/cJ MGP_BALBcJ_G0030048
 protein coding gene Chr5:123285100-123305290 (+)
C3H/HeJ MGP_C3HHeJ_G0029765
 protein coding gene Chr5:126501052-126520516 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030501
 protein coding gene Chr5:132154222-132179883 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027727
 protein coding gene Chr5:116498729-116519586 (+)
CAST/EiJ MGP_CASTEiJ_G0029174
 protein coding gene Chr5:125595554-125617034 (+)
CBA/J MGP_CBAJ_G0029735
 protein coding gene Chr5:137348467-137378055 (+)
DBA/2J MGP_DBA2J_G0029885
 protein coding gene Chr5:121970330-121990389 (+)
FVB/NJ MGP_FVBNJ_G0029841
 protein coding gene Chr5:120999177-121017904 (+)
LP/J MGP_LPJ_G0029974
 protein coding gene Chr5:127764942-127790388 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029872
 protein coding gene Chr5:140981147-141014207 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030542
 protein coding gene Chr5:125476726-125496275 (+)
PWK/PhJ MGP_PWKPhJ_G0028888
 protein coding gene Chr5:120774749-120795970 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028725
 protein coding gene Chr5:123147763-123176603 (+)
WSB/EiJ MGP_WSBEiJ_G0029249
 protein coding gene Chr5:126140461-126168938 (+)



Homology
more
  • Human Ortholog
    LRRC43, leucine rich repeat containing 43
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LRRC43, leucine rich repeat containing 43
  • Links
    NCBI Gene ID: 254050
    neXtProt AC: NX_Q8N309
    UniProt: Q8N309

  • Chr Location
    12q24.31; chr12:122167719-122203471 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    7
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000063409 Ensembl Gene Model | MGI Sequence Detail 18901 C57BL/6J ±  kb
transcript ENSMUST00000094327 Ensembl | MGI Sequence Detail 2046 Not Applicable  
polypeptide ENSMUSP00000091885 Ensembl | MGI Sequence Detail 667 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000032491 leucine-rich repeat-containing protein 43
    (term hierarchy)
  • InterPro Domains
    IPR050576 Ciliary and flagellar integrity-associated protein
    IPR032675 Leucine-rich repeat domain superfamily
Molecular
Reagents
less
  • All nucleic 7
    cDNA 7

    Microarray probesets 1
References
more
  • Summaries
    All 23
    Phenotypes 8
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory