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Bex4 Gene Detail
Summary
  • Symbol
    Bex4
  • Name
    brain expressed X-linked 4
  • Feature Type
    protein coding gene
  • IDs
    MGI:3606746
    NCBI Gene: 406217
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:135039745-135041192 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 57.40 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    118 from dbSNP Build 142
  • Strain Annotations
    14
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3606746
 protein coding gene ChrX:135039745-135041192 (+)
129S1/SvImJ MGP_129S1SvImJ_G0016573
 protein coding gene Chr1:154909351-154911355 (-)
A/J MGP_AJ_G0018310
 protein coding gene Chr11:55423229-55430703 (-)
AKR/J MGP_AKRJ_G0018279
 protein coding gene Chr11:57244066-57244510 (-)
BALB/cJ MGP_BALBcJ_G0018281
 protein coding gene Chr11:55765027-55765641 (-)
C3H/HeJ MGP_C3HHeJ_G0035773
 protein coding gene ChrX:133490353-133490962 (+)
C57BL/6NJ no annotation
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0017657
 protein coding gene Chr11:57259262-57262066 (-)
CBA/J MGP_CBAJ_G0018067
 protein coding gene Chr11:62098033-62098607 (-)
DBA/2J MGP_DBA2J_G0018176
 protein coding gene Chr11:55070139-55070753 (-)
FVB/NJ no annotation
LP/J MGP_LPJ_G0018251
 protein coding gene Chr11:58131518-58138302 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035874
 protein coding gene ChrX:148954431-148955878 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0018775
 protein coding gene Chr11:57269628-57274532 (-)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0034584
 protein coding gene ChrX:115060882-115062391 (+)
WSB/EiJ MGP_WSBEiJ_G0035195
 protein coding gene ChrX:131189786-131191240 (+)



Homology
more
  • Human Ortholog
    BEX4, brain expressed X-linked 4
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    BEX4, brain expressed X-linked 4
  • Synonyms
    BEXL1
  • Links
    NCBI Gene ID: 56271
    neXtProt AC: NX_Q9NWD9
    UniProt: Q9NWD9

  • Chr Location
    Xq22.1; chrX:103215092-103217246 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    27
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    873
  • Tissues
    60
  • cDNA Data
    34
  • Literature Summary
    8
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 406217 NCBI Gene Model | MGI Sequence Detail 1448 C57BL/6J ±  kb
transcript NM_212457 RefSeq | MGI Sequence Detail 859 C57BL/6  
polypeptide Q9CWT2 UniProt | EBI | MGI Sequence Detail 118 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 37
    cDNA 34
    Primer pair 2
    Other 1

    Microarray probesets 3
References
more
  • Summaries
    All 38
    Developmental Gene Expression 8
    Gene Ontology 7
    Phenotypes 8
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory