About   Help   FAQ
Mir7-1 Gene Detail
Summary
  • Symbol
    Mir7-1
  • Name
    microRNA 7-1
  • Synonyms
    mir 7-1, miR-7a1, Mir7a1, Mirn7-1, mmu-mir-7-1, mmu-mir-7a-1, mmu-miR-7a1
  • Feature Type
    miRNA gene
  • IDs
    MGI:3619436
    NCBI Gene: 723902
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:58540593-58540700 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 31.04 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    31 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3619436
 miRNA gene Chr13:58540593-58540700 (-)
129S1/SvImJ MGP_129S1SvImJ_G0008074
 miRNA gene Chr13:58032943-58033050 (-)
A/J MGP_AJ_G0008063
 miRNA gene Chr13:55878577-55878684 (-)
AKR/J MGP_AKRJ_G0008041
 miRNA gene Chr13:57540825-57540932 (-)
BALB/cJ MGP_BALBcJ_G0008044
 miRNA gene Chr13:56138117-56138224 (-)
C3H/HeJ MGP_C3HHeJ_G0007988
 miRNA gene Chr13:57349656-57349763 (-)
C57BL/6NJ MGP_C57BL6NJ_G0008228
 miRNA gene Chr13:59815407-59815514 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0007337
 miRNA gene Chr13:53771662-53771769 (-)
CAST/EiJ MGP_CASTEiJ_G0007874
 miRNA gene Chr13:57482559-57482666 (-)
CBA/J MGP_CBAJ_G0007958
 miRNA gene Chr13:62064651-62064758 (-)
DBA/2J MGP_DBA2J_G0007992
 miRNA gene Chr13:55429705-55429812 (-)
FVB/NJ MGP_FVBNJ_G0008013
 miRNA gene Chr13:54906694-54906801 (-)
LP/J MGP_LPJ_G0008074
 miRNA gene Chr13:58302587-58302694 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0007985
 miRNA gene Chr13:61424316-61424423 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0008228
 miRNA gene Chr13:57145737-57145844 (-)
PWK/PhJ MGP_PWKPhJ_G0007791
 miRNA gene Chr13:55437032-55437139 (-)
SPRET/EiJ MGP_SPRETEiJ_G0007688
 miRNA gene Chr13:56055449-56055556 (-)
WSB/EiJ MGP_WSBEiJ_G0007943
 miRNA gene Chr13:57579287-57579394 (-)



Homology
more
  • Human Ortholog
    MIR7-1, microRNA 7-1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR7-1, microRNA 7-1
  • Synonyms
    hsa-mir-7-1, mir-7-1, MIRN7-1
  • Links
    NCBI Gene ID: 407043

  • Chr Location
    chr9:83969748-83969857 (-)  GRCh38
  • Human Ortholog
    MIR7-2, microRNA 7-2
  • Synonyms
    hsa-mir-7-2, mir-7-2, MIRN7-2
  • Links
    NCBI Gene ID: 407044

  • Chr Location
    chr15:88611825-88611934 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from multigenic genotypes
    10 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Targeted
    3
  • Genomic Mutations
    1 involving Mir7-1
  • Find Mice (IMSR)
    3 strains or lines available
Mice homozygous for a knock-out allele of Mir7-1 and Mir7b are born in expected Mendelian frequency and are grossly normal.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    17
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    877
  • Tissues
    59
  • Literature Summary
    19
Sequences &
Gene Models
less
  • All Sequences
    23
  • RefSeq
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic 723902 NCBI Gene Model | MGI Sequence Detail 108 C57BL/6J ±  kb
transcript NR_029825 RefSeq | MGI Sequence Detail 108 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 16
    Primer pair 9
    Other 7
Other Database
Links
less
miRBase MI0000728
References
more
  • Summaries
    All 53
    Developmental Gene Expression 19
    Gene Ontology 10
    Phenotypes 10
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:352077 Kane E, et al., MicroRNA-7 regulates endocrine progenitor delamination and endocrine cell mass in developing pancreatic islets. iScience. 2024 Jul 19;27(7):110332
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
10/22/2024
MGI 6.24 		The Jackson Laboratory