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Gbp10 Gene Detail
Summary
  • Symbol
    Gbp10
  • Name
    guanylate-binding protein 10
  • Feature Type
    protein coding gene
  • IDs
    MGI:4359647
    NCBI Gene: 626578
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:105363565-105387399 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 50.68 cM
Strain
Comparison
more
  • SNPs within 2kb
    264 from dbSNP Build 142
  • Strain Annotations
    7
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_4359647
 protein coding gene Chr5:105363565-105387399 (-)
129S1/SvImJ no annotation
A/J MGP_AJ_G0029788
 protein coding gene Chr5:102920738-102921349 (-)
AKR/J no annotation
BALB/cJ no annotation
C3H/HeJ MGP_C3HHeJ_G0029522
 protein coding gene Chr5:106864779-106884111 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030252
 protein coding gene Chr5:111581837-111605106 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027489
 protein coding gene Chr5:98147863-98219926 (-)
CAST/EiJ MGP_CASTEiJ_G0028936
 protein coding gene Chr5:105808280-105830843 (-)
CBA/J no annotation
DBA/2J no annotation
FVB/NJ no annotation
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ no annotation
PWK/PhJ MGP_PWKPhJ_G0028647
 protein coding gene Chr5:101376520-101648862 (-)
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    GBP6, guanylate binding protein family member 6
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GBP6, guanylate binding protein family member 6
  • Links
    NCBI Gene ID: 163351
    neXtProt AC: NX_Q6ZN66
    UniProt: Q6ZN66

  • Chr Location
    1p22.2; chr1:89364059-89388160 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    843
  • Tissues
    17
  • cDNA Data
    3
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 626578 NCBI Gene Model | MGI Sequence Detail 23835 C57BL/6J ±  kb
transcript NM_001039646 RefSeq | MGI Sequence Detail 3528 C57BL/6  
polypeptide NP_001034735 RefSeq | MGI Sequence Detail 611 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR030386 GB1/RHD3-type guanine nucleotide-binding (G) domain
    IPR003191 Guanylate-binding protein/Atlastin, C-terminal
    IPR037684 Guanylate-binding protein, C-terminal
    IPR036543 Guanylate-binding protein, C-terminal domain superfamily
    IPR015894 Guanylate-binding protein, N-terminal
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
Molecular
Reagents
less
  • All nucleic 4
    cDNA 4
References
more
  • Summaries
    All 20
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 7
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:172364 Kim BH, et al., A family of IFN-gamma-inducible 65-kD GTPases protects against bacterial infection. Science. 2011 May 6;332(6030):717-21
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/22/2024
MGI 6.24 		The Jackson Laboratory