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Crabp1 Gene Detail
Summary
  • Symbol
    Crabp1
  • Name
    cellular retinoic acid binding protein I
  • Synonyms
    Crabp-1, CrabpI, Rbp-5
  • Feature Type
    protein coding gene
  • IDs
    MGI:88490
    NCBI Gene: 12903
  • Alliance
    gene page
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:54672032-54680394 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 29.76 cM
  • Mapping Data
    10 experiments
Strain
Comparison
more
  • SNPs within 2kb
    317 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_88490
 protein coding gene Chr9:54672032-54680394 (+)
129S1/SvImJ MGP_129S1SvImJ_G0034830
 protein coding gene Chr9:53826756-53835254 (+)
A/J MGP_AJ_G0034811
 protein coding gene Chr9:52102738-52111093 (+)
AKR/J MGP_AKRJ_G0034740
 protein coding gene Chr9:53285997-53296961 (+)
BALB/cJ MGP_BALBcJ_G0034803
 protein coding gene Chr9:51877249-51885598 (+)
C3H/HeJ MGP_C3HHeJ_G0034513
 protein coding gene Chr9:53749097-53758224 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035322
 protein coding gene Chr9:55325722-55334084 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032234
 protein coding gene Chr9:51521864-51530194 (+)
CAST/EiJ MGP_CASTEiJ_G0033835
 protein coding gene Chr9:53776720-53786089 (+)
CBA/J MGP_CBAJ_G0034484
 protein coding gene Chr9:57246507-57254840 (+)
DBA/2J MGP_DBA2J_G0034643
 protein coding gene Chr9:51995524-52003913 (+)
FVB/NJ MGP_FVBNJ_G0034585
 protein coding gene Chr9:51197138-51206143 (+)
LP/J MGP_LPJ_G0034726
 protein coding gene Chr9:54139982-54150455 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0034628
 protein coding gene Chr9:58786299-58794666 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035344
 protein coding gene Chr9:53297518-53305878 (+)
PWK/PhJ MGP_PWKPhJ_G0033539
 protein coding gene Chr9:51978195-51986571 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033374
 protein coding gene Chr9:53560541-53568828 (+)
WSB/EiJ MGP_WSBEiJ_G0033947
 protein coding gene Chr9:53267286-53275625 (+)



Homology
more
  • Human Ortholog
    CRABP1, cellular retinoic acid binding protein 1
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CRABP1, cellular retinoic acid binding protein 1
  • Synonyms
    CRABP, CRABP-I, CRABPI, RBP5
  • Links
    NCBI Gene ID: 1381
    neXtProt AC: NX_P29762
    UniProt: P29762

  • Chr Location
    15q25.1; chr15:78340353-78348225 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 3 alleles in 3 genetic backgrounds
    3 phenotypes from multigenic genotypes
    21 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygotes for targeted null mutations are phenotypically normal and fertile.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    2080
  • Tissues
    694
  • cDNA Data
    52
  • Literature Summary
    201
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 12903 NCBI Gene Model | MGI Sequence Detail 8363 C57BL/6J ±  kb
    transcript NM_013496 RefSeq | MGI Sequence Detail 819 ZRU/MplStud  
    polypeptide P62965 UniProt | EBI | MGI Sequence Detail 137 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 103
      Genomic 8
      cDNA 57
      Primer pair 14
      Other 24

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGD-MRK-13791, MGD-MRK-2126, MGD-MRK-2128, MGI:2143024
    References
    more
    • Summaries
      All 259
      Developmental Gene Expression 201
      Gene Ontology 5
      Phenotypes 21
    • Earliest
      J:9912 Vaessen MJ, et al., Preferential expression of cellular retinoic acid binding protein in a subpopulation of neural cells in the developing mouse embryo. Differentiation. 1989 May;40(2):99-105
    • Latest
      J:349865 Carabana C, et al., Spatially distinct epithelial and mesenchymal cell subsets along progressive lineage restriction in the branching embryonic mammary gland. EMBO J. 2024 Jun;43(12):2308-2336
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/19/2024
    MGI 6.24     		The Jackson Laboratory