Cryge^ns
Spontaneous Allele Detail

Summary

• Symbol: Cryge^ns
• Name: crystallin, gamma E; dominant cataract 2, nuclear and anterior suture opacity
• MGI ID: MGI:1855994
• Synonyms: Cat2^ns, Cryge^Cat2-ns, K-134, Scat
• Gene: Cryge Location: Chr1:65087713-65090308 bp, - strand Genetic Position: Chr1, 32.8 cM
• Alliance: Cryge^ns page

Mutation origin

• Strain of Origin: (101/El x C3H/El)F1

Mutation description

• Allele Type: Spontaneous
• Mutation: Intragenic deletion
• Mutation details: This mutation, originally called Scat, arose in a breeding colony at Neuherberg in 1989. Molecular analysis revealed a large deletion within the third exon of the gene. (J:53767)
• Inheritance: Semidominant

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Cryge Mutation: 25 strains or lines available

References

• Original: J:83039 Graw J, et al., Characterization of Scat (suture cataract), a dominant cataract mutation in mice. Exp Eye Res. 1989 Sep;49(3):469-77
• All: 5 reference(s)