Crygf^Rop
Chemically induced Allele Detail

Summary

• Symbol: Crygf^Rop
• Name: crystallin, gamma F; dominant cataract 2, radial opacity
• MGI ID: MGI:1855996
• Synonyms: Cat2^ro, Crygf^Cat2-ro, rop
• Gene: Crygf Location: Chr1:65965679-65967466 bp, + strand Genetic Position: Chr1, 33.31 cM, cytoband C3
• Alliance: Crygf^Rop page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Chemically induced (other)
• Mutation: Single point mutation
• Mutation details: A T-to-A transversion in exon 2 of the gene is predicted to result in a Val to Glu exchange in codon 38 of the encoded protein. (J:78760)
• Inheritance: Semidominant

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Crygf Mutation: 8 strains or lines available

References

• Original: J:24033 Kratochvilova J, et al., Dominant cataract and recessive specific-locus mutations detected in offspring of procarbazine-treated male mice. Mutat Res. 1988 Apr;198(2):295-301
• All: 3 reference(s)