Cdk5rap2^an
Radiation induced Allele Detail

Summary

• Symbol: Cdk5rap2^an
• Name: CDK5 regulatory subunit associated protein 2; Hertwig's anemia
• MGI ID: MGI:1856646
• Gene: Cdk5rap2 Location: Chr4:70135092-70328672 bp, - strand Genetic Position: Chr4, 35.92 cM, cytoband C2
• Alliance: Cdk5rap2^an page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Radiation induced (Modified isoform(s))
• Mutations: Intragenic deletion, Inversion
• Mutation details: Exon 4 is inverted which results in an in-frame 111 bp deletion with the loss of exon 4 from the mRNA. Northern analysis demonstrated that exon 4 was uniformly omitted from the mutant mRNA. (J:160533)
• Inheritance: Recessive

Disease models

Expression

In Structures Affected by this Mutation:

11 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 3 strains available Cell Lines: 0 lines available
• Carrying any Cdk5rap2 Mutation: 87 strains or lines available

References

• Original: J:208 Hertwig P, Neue Mutationen und Koppelungsgruppen bei der Hausmaus. Z Indukt Abstamm Vererbungsl. 1942;80(1):220-246
• All: 21 reference(s)