Sry^dl1Rlb
Spontaneous Allele Detail

Summary

• Symbol: Sry^dl1Rlb
• Name: sex determining region of Chr Y; sex determining region of Chr Y-deletion 1, Robin Lovell-Badge
• MGI ID: MGI:1857786
• Synonyms: Sry^dl1Rob, Sry^m1, Tdy^m1, Y-, Yq-del, Y^Tdym1
• Gene: Sry Location: ChrY:2662471-2663658 bp, - strand Genetic Position: ChrY, cytoband p
• Alliance: Sry^dl1Rlb page

Mutation origin

• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Spontaneous
• Mutation: Intragenic deletion
• Mutation details: This allele contains an 11 kb deletion in the testis-determining region of the gene, including a highly conserved exon encoding the HMG box domain. (J:2258)
• Inheritance: Semidominant

Expression

In Mice Carrying this Mutation:	33 assay results 3 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Sry Mutation: 54 strains or lines available

References

• Original: J:10734 Lovell-Badge R, et al., XY female mice resulting from a heritable mutation in the primary testis-determining gene, Tdy. Development. 1990 Jul;109(3):635-46
• All: 74 reference(s)