Myf5^tm3(cre)Sor
Targeted Allele Detail

Summary

• Symbol: Myf5^tm3(cre)Sor
• Name: myogenic factor 5; targeted mutation 3, Philippe Soriano
• MGI ID: MGI:2135565
• Synonyms: Mif5-Cre, Myf5^Cre, Myf5^Cre-So, Myf5^CreSOR, myf5-CreTG
• Gene: Myf5 Location: Chr10:107318769-107321995 bp, - strand Genetic Position: Chr10, 55.95 cM
• Alliance: Myf5^tm3(cre)Sor page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:65301
• Parent Cell Line: AK7 (ES Cell)
• Strain of Origin: 129S4/SvJaeSor

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Myf5^tm3(cre)Sor expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Myf5 (MGI:97252)

• Mutation details: A cre cDNA was inserted between a SacI site and a KpnI site in the 5'UTR of the Myf5 gene. An adjacent loxP-flanked neomycin cassette was removed by Cre- mediated recombination. (J:65301)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Myf5 (mouse) Summary of all recombinase alleles driven by Myf5. Comparative matrix view of recombinase activities Alliance mouse Myf5 gene page

Disease models

Expression

In Mice Carrying this Mutation:	316 assay results 7 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Myf5 Mutation: 17 strains or lines available

References

• Original: J:65301 Tallquist MD, et al., Early myotome specification regulates PDGFA expression and axial skeleton development. Development. 2000 Dec;127(23):5059-70
• All: 158 reference(s)