Gt(ROSA)26Sor^tm1(EYFP)Cos
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^tm1(EYFP)Cos
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Frank Costantini
• MGI ID: MGI:2449038
• Synonyms: Gt(ROSA)26Sor-StopFlox-EYFP, LSLYFP, R26eYFP, R26::EYFP, R26R^eYFP, R26ReYFP, R26R EYFP, R26R-EYFP, R26R^YFP, R26RYFP, R26-stop-EYFP, R26Y, r26YFP, R26-YFP, R26YY, R-EYFP, ROSA26-EYFP, Rosa26-eYFP^tg, ROSA26^floxSTOP^floxYFP, ROSA26^floxSTOP-YFP, ROSA26-LoxP-STOP-LoxP-EYFP, ROSA26-loxP-Stop-loxP-YF, ROSA26-lsl-EYFP, Rosa26^LSL-YFP, Rosa26R(YFP), ROSA26R-YFP, Rosa26^stopfloxYFP, Rosa26-Stop^fl-YFP, ROSA26-stop-YFP reporter, Rosa26YFP, ROSA26-YFP, Rosa26-YFP^fl, Rosa26-YFP^st, Rosa26^YFPStop, ROSA^EYFP, ROSA-LSL-YFP, ROSA-YFP, Rosa-YFP^f, RYR, YFP
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^tm1(EYFP)Cos page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:80963
• Parent Cell Line: JM-1 (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

Allele Type: Targeted (Conditional ready, Reporter) Mutation: Insertion Mutation details: A construct containing a floxed PGK-neo cassette and an enhanced yellow fluorescent protein (EYFP) gene was inserted into the Gt(ROSA)26Sor locus via homologous recombination. The floxed neo cassette contains a strong tpA stop sequence which prevents the transcription of EYFP. (J:80963)

Generation of Gt(ROSA)26Sor^tm1(EYFP)Cos or Gt(ROSA)26Sor^tm2(ECFP)Cos.

Expression

In Mice Carrying this Mutation:

104976 assay results 54 RNA-Seq or microarray experiment(s)

Tumor Data

List all tumor models in MMHCdb carrying Gt(ROSA)26Sor^tm1(EYFP)Cos

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 11 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 993 strains or lines available

References

• Original: J:80963 Srinivas S, et al., Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus. BMC Dev Biol. 2001;1(1):4
• All: 2392 reference(s)