Tg(CD2-icre)4Kio
Transgene Detail

Summary

• Symbol: Tg(CD2-icre)4Kio
• Name: transgene insertion 4, Dimitris Kioussis
• MGI ID: MGI:2449947
• Synonyms: CD2-Cre, hCD2-Cre, hCD2-iCre, Tg(CD2-cre)1Kio, Tg(CD2-cre)4Kio
• Transgene: Tg(CD2-icre)4Kio Location: unknown
• Alliance: Tg(CD2-icre)4Kio page

Transgene origin

• Strain of Origin: (CBA/Ca x C57BL/10)F2

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(CD2-icre)4Kio expression driven by 1 gene
  Transgene expression driven by:
  

  Organism

  Driver Gene

  Homolog in Mouse

  Note

  human

  CD2 (914)

  Cd2	(MGI:88320)

• Mutation details: This transgene expresses Cre recombinase under the control of a human CD2 promoter. The promoter was shown to be active in lymph nodes, thymus, spleen, Peyer's patches, intestinal cryptopatches and testes. (J:81568)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	CD2 (human) Summary of all recombinase alleles driven by CD2. Comparative matrix view of recombinase activities Alliance human CD2 gene page

Disease models

Expression

In Mice Carrying this Mutation:

5 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 5 strains available Cell Lines: 0 lines available

References

• Original: J:81568 De Boer J, et al., Transgenic mice with hematopoietic and lymphoid specific expression of Cre. Eur J Immunol. 2003 Feb;33(2):314-25
• All: 89 reference(s)