Mgmt^tm1Iz
Targeted Allele Detail

Summary

• Symbol: Mgmt^tm1Iz
• Name: O-6-methylguanine-DNA methyltransferase; targeted mutation 1, Manfred F Rajewsky
• MGI ID: MGI:2652462
• Synonyms: AGT^flox
• Gene: Mgmt Location: Chr7:136496343-136731995 bp, + strand Genetic Position: Chr7, 82.07 cM
• Alliance: Mgmt^tm1Iz page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:82357
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• The last exon of the gene was flanked by inserted loxP sites. (J:82357)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Mgmt Mutation: 29 strains or lines available

References

• Original: J:82357 Schweer T, et al., Conditional liver-specific "knock-out" of the murine genes encoding 06-Alkylguanine-DNA Alkyltransferase (AGT) and AP-Endonuclease (APE). J Biomol Struct Dyn. 1998;16:180-1 (Abstr.)
• All: 1 reference(s)