Prkcq^tm1Bai
Targeted Allele Detail

Summary

• Symbol: Prkcq^tm1Bai
• Name: protein kinase C, theta; targeted mutation 1, Gottfried Baier
• MGI ID: MGI:2664370
• Synonyms: PKCThetaflox, PKCTheta^flox
• Gene: Prkcq Location: Chr2:11176922-11306033 bp, + strand Genetic Position: Chr2, 8.42 cM
• Alliance: Prkcq^tm1Bai page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:83733
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A 10 kb region including exons 3 and 4 was flanked by floxed neo cassette intron 2 and single loxP site in intron 4. (J:83733)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prkcq Mutation: 51 strains or lines available

References

• Original: J:83733 Pfeifhofer C, et al., Protein kinase C theta affects Ca2+ mobilization and NFAT cell activation in primary mouse T cells. J Exp Med. 2003 Jun 2;197(11):1525-35
• All: 2 reference(s)