Ifnar2^tm1Pjh
Targeted Allele Detail

Summary

• Symbol: Ifnar2^tm1Pjh
• Name: interferon (alpha and beta) receptor 2; targeted mutation 1, Paul J Hertzog
• MGI ID: MGI:2680693
• Synonyms: muIfnar2-
• Gene: Ifnar2 Location: Chr16:91169671-91202477 bp, + strand Genetic Position: Chr16, 52.82 cM
• Alliance: Ifnar2^tm1Pjh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:66964
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: Exon 4 was targeted, generating a null allele for both transmembrane and soluble isoforms of this gene. (J:66964, J:112593)

Expression

In Mice Carrying this Mutation:	1 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 4 strains available Cell Lines: 0 lines available
• Carrying any Ifnar2 Mutation: 42 strains or lines available

References

• Original: J:66964 Hardy MP, et al., The soluble murine type I interferon receptor Ifnar-2 is present in serum, is independently regulated, and has both agonistic and antagonistic properties. Blood. 2001 Jan 15;97(2):473-82
• All: 33 reference(s)