Im4^Bioz:BP1
QTL Variant Detail

Summary

• QTL variant: Im4^Bioz:BP1
• Name: immunoregulatory 4; Bioz:BP1
• MGI ID: MGI:3033074
• Synonyms: high antibody responder, Im4^H
• QTL: Im4 Location: Chr6:80461721-80461888 bp Genetic Position: Chr6, cM position of peak correlated region/allele: 35.13 cM
• QTL Note: genome coordinates based on the marker associated with the peak LOD score

Variant origin

• Strain of Specimen: Bioz:BP1

Variant description

• Allele Type: QTL
• Mutation: Undefined
• This allele confers increased antibody response compared to Bioz:MP1. (J:37251)
• Inheritance: Not Specified

Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:37251

High(H) and Low(L) antibody responder lines of Biozzi mice were used in mapping Im loci. (H x L)F1 x L mice were informative in mapping Im4 with D6Mit5.

References

• Original: J:37251 Puel A, et al., Toward genetic dissection of high and low antibody responsiveness in Biozzi mice. Proc Natl Acad Sci U S A. 1996 Dec 10;93(25):14742-6
• All: 1 reference(s)