Summary |
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Mutation origin |
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Mutation description |
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Phenotypes |
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View phenotypes and curated references for all genotypes (concatenated display).
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Expression |
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Find Mice (IMSR) |
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Notes |
Homozygous mutant mice display limb deformities and a low frequency of renal abnormalities, but not renal agenesis or aberrant lung patterning phenotypes. This mutation is a hypomorphic allele, allelic to Grem1tm1Azun. Compound heterozygous mutant mice show a fully penetrant "limb deformity" limb phenotype, but not the phenotypes causing neonatal lethality. Transcription was not detected in the limb bud mesenchyme of compound heterozygous mutant embryos (J:91385).
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References |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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