Tg(Igh2^k3-83)1Nemz
Transgene Detail

Summary

• Symbol: Tg(Igh2^k3-83)1Nemz
• Name: transgene insertion 3-83, David Nemazee
• MGI ID: MGI:3055213
• Synonyms: 3-83, 3-83mudelta, 3-83mudelta-TG, mudelta TG
• Transgene: Tg(Igh2^k3-83)1Nemz Location: unknown
• Alliance: Tg(Igh2^k3-83)1Nemz page

Transgene origin

• Strain of Origin: DBA/2 x (C57BL/10 x DBA/2)F2

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Igh2^k3-83)1Nemz expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Igh-Ia (MGI:106608)

• Mutation details: This immunoglobulin transgene (3-83 mu delta, anti-K-k,K-b) encodes antibody reactive with the membrane-bound H-2K(b) antigen. (J:76119, J:116735)

Tumor Data

List all tumor models in MMHCdb carrying Tg(Igh2^k3-83)1Nemz

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 3 strains available Cell Lines: 0 lines available

References

• Original: J:116735 Nemazee DA, et al., Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes. Nature. 1989 Feb 9;337(6207):562-6
• All: 23 reference(s)