Ppic^tm1Jsf
Targeted Allele Detail

Summary

• Symbol: Ppic^tm1Jsf
• Name: peptidylprolyl isomerase C; targeted mutation 1, Jeffrey S Friedman
• MGI ID: MGI:3512104
• Gene: Ppic Location: Chr18:53539413-53551079 bp, - strand Genetic Position: Chr18, 29.03 cM, cytoband D1
• Alliance: Ppic^tm1Jsf page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:94338
• Parent Cell Line: CJ7 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A GFP gene was fused in frame to the first exon. A floxed neo cassette replaced the rest of exon 1, exons 2 and 3, and part of exon 4. The floxed neo cassette was subsequently removed but the GFP gene was not functional. Immunohistochemistry, Western blot analysis, and Northern blot analysis confirm the absence of gene products. (J:94338)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ppic Mutation: 15 strains or lines available

References

• Original: J:94338 NIH Mouse Knockout Inventory, Information obtained from the NIH Mouse Knockout Inventory. MGI Direct Data Submission. 2004
• All: 1 reference(s)