Prdx1^{Gt(OST422296)Lex}
Gene trapped Allele Detail

Summary

• Symbol: Prdx1^{Gt(OST422296)Lex}
• Name: peroxiredoxin 1; gene trap OST422296, Lexicon Genetics
• MGI ID: MGI:3611932
• Synonyms: Prdx1^{Gt(betageo)706Lex}, Prx 1 ^-
• Gene: Prdx1 Location: Chr4:116542796-116557196 bp, + strand Genetic Position: Chr4, 53.28 cM
• Alliance: Prdx1^{Gt(OST422296)Lex} page

Mutation origin

• Mutant Cell Line: OST422296
• Germline Transmission: Earliest citation of germline transmission: J:103909
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: A gene trap vector was inserted into intron 3. Northern and Western blot analyses failed to detect mRNA and protein, respectively. (J:103909)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  OST422296	CG654382 ; (MGI Seq Detail)	3' RACE	Chr4:116550085-116556650 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  110 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prdx1 Mutation: 37 strains or lines available

References

• Original: J:103909 Uwayama J, et al., Tissue Prx I in the protection against Fe-NTA and the reduction of nitroxyl radicals. Biochem Biophys Res Commun. 2006 Jan 6;339(1):226-31
• All: 6 reference(s)