Tagln^tm2(cre)Yec
Targeted Allele Detail

Summary

• Symbol: Tagln^tm2(cre)Yec
• Name: transgelin; targeted mutation 2, Yuqing E Chen
• MGI ID: MGI:3706313
• Synonyms: Sm22alph^-, SM22alpha-creKI, Tagln^tm2(cre)Liw
• Gene: Tagln Location: Chr9:45840926-45847356 bp, - strand Genetic Position: Chr9, 25.36 cM
• Alliance: Tagln^tm2(cre)Yec page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:119865
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout, Recombinase)
• Mutation: Insertion
• Tagln^tm2(cre)Yec expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Tagln (MGI:106012)

• Mutation details: The cre recombinase coding sequence was inserted in frame into the initiation site, as well as a PGK-neo. (J:119865)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Tagln (mouse) Summary of all recombinase alleles driven by Tagln. Comparative matrix view of recombinase activities Alliance mouse Tagln gene page

Expression

In Mice Carrying this Mutation:

28 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Tagln Mutation: 28 strains or lines available

References

• Original: J:119865 Zhang J, et al., Generation of an adult smooth muscle cell-targeted Cre recombinase mouse model. Arterioscler Thromb Vasc Biol. 2006 Mar;26(3):e23-4
• All: 59 reference(s)