Foxe3^tm1Pca
Targeted Allele Detail

Summary

• Symbol: Foxe3^tm1Pca
• Name: forkhead box E3; targeted mutation 1, Peter Carlsson
• MGI ID: MGI:3707205
• Synonyms: Foxe3^tm
• Gene: Foxe3 Location: Chr4:114782344-114783210 bp, - strand Genetic Position: Chr4, 52.73 cM, cytoband C7
• Alliance: Foxe3^tm1Pca page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:119940
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• The forkhead box was replaced by a lacZ-PGK-neo cassette. (J:119940)

Expression

In Mice Carrying this Mutation:	10 assay results
In Structures Affected by this Mutation:	8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Foxe3 Mutation: 15 strains or lines available

References

• Original: J:119940 Blixt A, et al., Foxe3 is required for morphogenesis and differentiation of the anterior segment of the eye and is sensitive to Pax6 gene dosage. Dev Biol. 2007 Feb 1;302(1):218-29
• All: 3 reference(s)