Tg(C3-HA)142Dmp
Transgene Detail

Summary

• Symbol: Tg(C3-HA)142Dmp
• Name: transgene insertion 142, Drew M Pardoll
• MGI ID: MGI:3717261
• Transgene: Tg(C3-HA)142Dmp Location: unknown
• Alliance: Tg(C3-HA)142Dmp page

Transgene origin

• Strain of Origin: B10.D2-Hc⁰ H2^d H2-T18^c/oSnJ

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: The HA gene derived from the influenza virus A/PR/8/34 (Mount Sinai strain) has been placed under the control of the rat C3 promoter. Two founder lines were established. Line 142 contains three intact copies of the transgene and is expressed in many non=lymphatic tissues including the prostate, testes, heart, salivary gland, skeletal muscle, and the lung. (J:123134)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:123134 Adler AJ, et al., CD4+ T cell tolerance to parenchymal self-antigens requires presentation by bone marrow-derived antigen-presenting cells. J Exp Med. 1998 May 18;187(10):1555-64
• All: 3 reference(s)