Bex1^{Gt(OST125186)Lex}
Gene trapped Allele Detail

Summary

• Symbol: Bex1^{Gt(OST125186)Lex}
• Name: brain expressed X-linked 1; gene trap OST125186, Lexicon Genetics
• MGI ID: MGI:3764914
• Synonyms: Bex1-KO
• Gene: Bex1 Location: ChrX:135114721-135116262 bp, - strand Genetic Position: ChrX, 57.4 cM
• Alliance: Bex1^{Gt(OST125186)Lex} page

Mutation origin

• Mutant Cell Line: OST125186
• Germline Transmission: Earliest citation of germline transmission: J:127357
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: The gene trap vector inserted into intron 2. Western blot analysis confirmed the absence of protein expression and any gene trap fusion protein expression in tissue extracts from homozygous mice. (J:127357)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  OST125186	CG536826 ; (MGI Seq Detail)	3' RACE	ChrX:135114801-135115333 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  4 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Bex1 Mutation: 4 strains or lines available

References

• Original: J:127357 Koo JH, et al., Bex1 knock out mice show altered skeletal muscle regeneration. Biochem Biophys Res Commun. 2007 Nov 16;363(2):405-10
• All: 5 reference(s)