Plxnb1^tm1.1Ltam
Targeted Allele Detail

Summary

• Symbol: Plxnb1^tm1.1Ltam
• Name: plexin B1; targeted mutation 1.1, Luca Tamagnone
• MGI ID: MGI:3790773
• Synonyms: Plxnb1-
• Gene: Plxnb1 Location: Chr9:108924457-108948985 bp, + strand Genetic Position: Chr9, 59.63 cM
• Alliance: Plxnb1^tm1.1Ltam page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:134426
• Parent Cell Line: W9.5/W95 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Intragenic deletion
• Mutation details: Germ line, cre mediated deletion was used to remove exons 22 and 23. The absence of protein product was confirmed by western blot analysis on kidney and liver extracts. (J:134426)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Plxnb1 Mutation: 108 strains or lines available

References

• Original: J:134426 Fazzari P, et al., Plexin-B1 plays a redundant role during mouse development and in tumour angiogenesis. BMC Dev Biol. 2007;7:55
• All: 3 reference(s)