Ifit1^{tm1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Ifit1^{tm1(KOMP)Vlcg}
• Name: interferon-induced protein with tetratricopeptide repeats 1; targeted mutation 1, Velocigene
• MGI ID: MGI:3808310
• Synonyms: Ifit1^tm1Vlcg
• Gene: Ifit1 Location: Chr19:34618289-34627409 bp, + strand Genetic Position: Chr19, 29.78 cM
• Alliance: Ifit1^{tm1(KOMP)Vlcg} page
• IMPC: Ifit1 gene page

Mutation origin

• Mutant Cell Lines: 10542A-H6, 10542B-B6, 10542B-D8, 10542B-D12, 10542B-H8
• Germline Transmission: Earliest citation of germline transmission: J:187549
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

Allele Type: Targeted (Null/knockout, Reporter) Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1 Mutation details: A lacZ and floxed neo cassette replaced the coding sequence. Western blot analysis confirmed the absence of protein expression in mouse embryonic fibroblasts induced with IFN-beta. (J:136110, J:195382)

Generation of the Ifit1^tm1(KOMP)Vlcg allele

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 1 line available
• Carrying any Ifit1 Mutation: 22 strains or lines available

References

• Original: J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008
• All: 13 reference(s)