Ptpn3Gt(RRR573)Byg
Gene trapped Allele Detail
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Symbol: |
Ptpn3Gt(RRR573)Byg |
Name: |
protein tyrosine phosphatase, non-receptor type 3; gene trap RRR573, BayGenomics |
MGI ID: |
MGI:3830861 |
Synonyms: |
Ptpn3 deltaPTP, Ptpn3GtRRR573PdK |
Gene: |
Ptpn3 Location: Chr4:57190841-57301837 bp, - strand Genetic Position: Chr4, 31.66 cM
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Alliance: |
Ptpn3Gt(RRR573)Byg page
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Mutant Cell Line: |
RRR573 |
Germline Transmission: |
Earliest citation of germline transmission:
J:144280
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Parent Cell Line: |
E14TG2a.4 (ES Cell)
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Strain of Origin: |
129P2/OlaHsd
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Allele Type: |
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Gene trapped (Null/knockout) |
Mutation: |
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Insertion of gene trap vector
Vector: pGT0Lxf
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Mutation details: A betageo gene trap vector inserted into exon 27 of the locus where the nucleophilic cysteine residue necessary for enzymatic activity is encoded. No protein (endogenous or n-terminal portion of endogenous protein fused to betageo) was detected by immunoblot assays on homozygote brain extract.
(J:144280)
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Sequence Tags: |
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Sequence tag details (1 tag)
Tag ID |
GenBank ID |
Method |
Tag Location (trapped strand)* |
Select |
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Genome Context: |
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Genome Browser view of this mutation
126 gene trap insertions have trapped this gene
View all gene trap sequence tags in this region
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Ptpn3 Mutation: |
170 strains or lines available
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Original: |
J:144280 Bauler TJ, et al., Normal TCR signal transduction in mice that lack catalytically active PTPN3 protein tyrosine phosphatase. J Immunol. 2007 Mar 15;178(6):3680-7 |
All: |
2 reference(s) |
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