mt-Tr^m1
Spontaneous Allele Detail

Summary

• Symbol: mt-Tr^m1
• Name: mitochondrially encoded tRNA arginine; mutation 1
• MGI ID: MGI:3831887
• Synonyms: 10A
• Gene: mt-Tr Location: ChrMT:9808-9875 bp, + strand Genetic Position: ChrMT, Syntenic
• Alliance: mt-Tr^m1 page

Mutation origin

• Strain of Origin: various

Mutation description

• Allele Type: Spontaneous
• Mutation: Nucleotide repeat expansion
• The adenine repeat in the D stem is polymorphic with 10 adenines in this allele. (J:67312, J:97969)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 6 strains available Cell Lines: 0 lines available
• Carrying any mt-Tr Mutation: 10 strains or lines available

Notes

This polymorphism is present in A/J, NZB/B1NJ, ALS/Lt and NOD/ShiLtJ. A variant with 9 adenines is found in NOD/ShiLtDvs, ALR/Lt and SKH2/J.

References

• Original: J:67312 Johnson KR, et al., A nuclear-mitochondrial DNA interaction affecting hearing impairment in mice. Nat Genet. 2001 Feb;27(2):191-4
• All: 6 reference(s)