Tg(Cck-EGFP)BJ203Gsat
Transgene Detail

Summary

• Symbol: Tg(Cck-EGFP)BJ203Gsat
• Name: transgene insertion BJ203, GENSAT Project at Rockefeller University
• MGI ID: MGI:3840871
• Synonyms: Cck-eGFP, Cck-GFP, Founder Line BJ203, Tg(Cck-EGFP)1Gsat
• Transgene: Tg(Cck-EGFP)BJ203Gsat Location: unknown
• Alliance: Tg(Cck-EGFP)BJ203Gsat page

Transgene origin

• Strain of Origin: FVB/NTac
• Project Collection: GENSAT

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Mutation details: This transgene contains the coding sequence for enhanced green fluorescent protein (EGFP), followed by a polyadenylation signal, inserted into the mouse genomic bacterial artificial chromosome (BAC) RP23-234I17 at the ATG transcription initiation codon of the cholecystokinin (Cck) gene so that expression of the reporter mRNA/protein is driven by the regulatory sequences of the mouse gene. (J:100256)

Phenotypes

Key:

hm	homozygous	ht	heterozygous	tg	involves transgenes	√	phenotype observed
cn	conditional genotype	cx	complex: > 1 genome feature	ot	other: hemizygous, indeterminate,...	N	normal phenotype

Genotype/
Background:

	Allelic Composition	Genetic Background	Cell Line(s)
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cx1	Ildr1^Gt(D178D03)Wrst/Ildr1^Gt(D178D03)Wrst Tg(Cck-EGFP)BJ203Gsat/0	involves: 129S2/SvPas * C57BL/6J * FVB/NTac * Swiss Webster

Phenotypes:

Affected Systems	cx1
show or hide all annotated terms
digestive/alimentary system	√
abnormal intestinal epithelium morphology	√
homeostasis/metabolism	√
abnormal circulating hormone level	√

View phenotypes and curated references for all genotypes (concatenated display).

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

Notes

The modified bacterial artificial chromosome (BAC) BX374 was used to generate this transgenic line.

References

• Original: J:100296 Gong S, et al., A gene expression atlas of the central nervous system based on bacterial artificial chromosomes. Nature. 2003 Oct 30;425(6961):917-25
• All: 21 reference(s)