Mtm1^m1
Spontaneous Allele Detail

Summary

• Symbol: Mtm1^m1
• Name: X-linked myotubular myopathy gene 1; mutation 1
• MGI ID: MGI:3848518
• Gene: Mtm1 Location: ChrX:70254373-70359019 bp, + strand Genetic Position: ChrX, 36.55 cM
• Alliance: Mtm1^m1 page

Mutation origin

• Strain of Origin: multiple strains

Mutation description

Allele Type: Spontaneous Mutation: Transposon insertion Mutation details: A MusD/Early transposon family insertion of 5500bp occurred in the sense orientation in intron 8 at position 67552081 on the X chromosome (version mm8). This mutation is found in A/J, A/WySn, C3H, and BALB/c mice. mRNA expression is reduced by about 75%. (J:149430, J:149432)

Schematic of the location of the transposon insertion generating the Mtm1^m1 allele

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mtm1 Mutation: 27 strains or lines available

References

• Original: J:149432 Zhang Y, et al., Genome-wide assessments reveal extremely high levels of polymorphism of two active families of mouse endogenous retroviral elements. PLoS Genet. 2008 Feb;4(2):e1000007
• All: 2 reference(s)