mt-Atp8^m1
Spontaneous Allele Detail

Summary

• Symbol: mt-Atp8^m1
• Name: mitochondrially encoded ATP synthase 8; mutation 1
• MGI ID: MGI:4355536
• Synonyms: mt-Atp8^FVB/NJ
• Gene: mt-Atp8 Location: ChrMT:7766-7969 bp, + strand Genetic Position: ChrMT, Syntenic
• Alliance: mt-Atp8^m1 page

Mutation origin

• Strain of Origin: FVB/NJ

Mutation description

• Allele Type: Spontaneous
• Mutation: Single point mutation
• Mutation details: A G-to-T transversion is located at nucleotide 7778 resulting in an aspartic acid to tyrosine substitution in the fifth amino acid of the conserved N-terminus of the protein (p.D5Y). This substitution has been reported in the FVB/NJ strain. (J:143901)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 6 strains available Cell Lines: 0 lines available
• Carrying any mt-Atp8 Mutation: 6 strains or lines available

References

• Original: J:143901 Yu X, et al., Dissecting the effects of mtDNA variations on complex traits using mouse conplastic strains. Genome Res. 2009 Jan;19(1):159-65
• All: 9 reference(s)