Ube2u^{tm1e(KOMP)Wtsi}
Targeted Allele Detail

Summary

• Symbol: Ube2u^{tm1e(KOMP)Wtsi}
• Name: ubiquitin-conjugating enzyme E2U (putative); targeted mutation 1e, Wellcome Trust Sanger Institute
• MGI ID: MGI:4363149
• Gene: Ube2u Location: Chr4:100336064-100407342 bp, + strand Genetic Position: Chr4, 45.72 cM
• Alliance: Ube2u^{tm1e(KOMP)Wtsi} page
• IMPC: Ube2u gene page

Mutation origin

• Mutant Cell Lines: EPD0036_4_A05, EPD0036_4_A06, EPD0036_4_D05, EPD0036_4_F06, EPD0036_4_G04, EPD0036_4_G05
• Germline Transmission: Earliest citation of germline transmission: J:204812
• Parent Cell Line: JM8.F6 (ES Cell)
• Strain of Origin: C57BL/6N
• Project Collection: KOMP-CSD

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion Vector: L1L2_gt0
• Mutation details: The L1L2_gt0 cassette was inserted at position 100346823 of Chromosome 4 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT flanked lacZ/neomycin sequence followed by a loxP site. Insertion of this cassette creates a reporter knockout mouse. Cre expression will remove the neomycin selection cassette. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml (J:148605, J:173534)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 2 lines available
• Carrying any Ube2u Mutation: 33 strains or lines available

References

• Original: J:148605 Wellcome Trust Sanger Institute, Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2009
• All: 3 reference(s)