Dip2b^{tm1e(EUCOMM)Wtsi}
Targeted Allele Detail

Summary

• Symbol: Dip2b^{tm1e(EUCOMM)Wtsi}
• Name: disco interacting protein 2 homolog B; targeted mutation 1e, Wellcome Trust Sanger Institute
• MGI ID: MGI:4432503
• Gene: Dip2b Location: Chr15:99936545-100117354 bp, + strand Genetic Position: Chr15, 56.14 cM
• IMPC: Dip2b gene page

Mutation origin

• Mutant Cell Lines: EPD0113_2_A12, EPD0113_2_B12, EPD0113_2_E10, EPD0113_2_E12, EPD0113_2_G11, EPD0113_2_H10, EPD0113_2_H11
• Germline Transmission: Unknown
• Parent Cell Line: JM8.N4 (ES Cell)
• Strain of Origin: C57BL/6N
• Project Collection: EUCOMM

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion Vector: L1L2_gt1
• Mutation details: The L1L2_gt1 cassette was inserted at position 100054583 of Chromosome 15 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT flanked lacZ/neomycin sequence followed by a loxP site. Insertion of this cassette creates a reporter knockout mouse. Cre expression will remove the neomycin selection cassette. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml (J:155845, J:173534)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 1 line available
• Carrying any Dip2b Mutation: 138 strains or lines available

References

• Original: J:155845 Wellcome Trust Sanger Institute, Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2010
• All: 2 reference(s)