Tg(tetO-Cd74/MCC)#Doi
Transgene Detail
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| Symbol: |
Tg(tetO-Cd74/MCC)#Doi |
| Name: |
transgene insertion #, Christophe Benoist and Diane Mathis |
| MGI ID: |
MGI:4439134 |
| Synonyms: |
TIM |
| Transgene: |
Tg(tetO-Cd74/MCC)#Doi Location: unknown
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| Alliance: |
Tg(tetO-Cd74/MCC)#Doi page
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| Strain of Origin: |
(C57BL/6 x SJL)F2
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| Transgene Type: |
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Transgenic (Inducible, Inserted expressed sequence) |
| Inducer: |
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doxycycline/tetracycline |
| Mutation: |
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Insertion
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Mutation details: Seven tetO sequences were combined with the CMV minimal promoter to drive expression, when induced by doxycycline, of a construct composed of the Cd74 cDNA and a segment of moth cytochrome c DNA encoding amino acid residues 93 to 103 replacing the CLIP region of Cd74, encoding amino acid residues 88 to 98.
(J:94535)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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| Original: |
J:94535 van Santen HM, et al., Number of T reg cells that differentiate does not increase upon encounter of agonist ligand on thymic epithelial cells. J Exp Med. 2004 Nov 15;200(10):1221-30 |
| All: |
6 reference(s) |
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Analysis Tools
