Tg(Cd74-rtTA)#Doi
Transgene Detail

Summary

• Symbol: Tg(Cd74-rtTA)#Doi
• Name: transgene insertion, Christophe Benoist and Diane Mathis
• MGI ID: MGI:4439138
• Synonyms: Ii-rTA
• Transgene: Tg(Cd74-rtTA)#Doi Location: unknown
• Alliance: Tg(Cd74-rtTA)#Doi page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Transactivator)
• Mutation: Insertion
• Mutation details: The Cd74 promoter, together with the H2-Ea enhancer, was used to drive expression of an improved reverse tet transactivator, rtTZ-S2. Four independent lines were produced. An un-named line showing the lowest liver expression was used. (J:158562)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:158562 Obst R, et al., Antigen persistence is required throughout the expansion phase of a CD4(+) T cell response. J Exp Med. 2005 May 16;201(10):1555-65
• All: 5 reference(s)