Tg(tetO-Tyr)1335Lmon
Transgene Detail

Summary

• Symbol: Tg(tetO-Tyr)1335Lmon
• Name: transgene insertion 1335, Lluis Montoliu
• MGI ID: MGI:4443329
• Transgene: Tg(tetO-Tyr)1335Lmon Location: unknown
• Alliance: Tg(tetO-Tyr)1335Lmon page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inducible, Inserted expressed sequence)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Mutation details: A tetO construct was used to control the expression of full-length mouse cDNA for Tyr. Four founders were identified, three of which transmitted the transgene through the germline. (J:92358)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available

References

• Original: J:92358 Gimenez E, et al., A transgenic mouse model with inducible Tyrosinase gene expression using the tetracycline (Tet-on) system allows regulated rescue of abnormal chiasmatic projections found in albinism. Pigment Cell Res. 2004 Aug;17(4):363-70
• All: 1 reference(s)