Jmjd8^{tm1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Jmjd8^{tm1(KOMP)Vlcg}
• Name: jumonji domain containing 8; targeted mutation 1, Velocigene
• MGI ID: MGI:4452995
• Gene: Jmjd8 Location: Chr17:26048017-26050817 bp, + strand Genetic Position: Chr17, 12.92 cM, cytoband B1
• Alliance: Jmjd8^{tm1(KOMP)Vlcg} page
• IMPC: Jmjd8 gene page

Mutation origin

• Mutant Cell Lines: 13985A-A2, 13985A-A5, 13985A-C12, 13985A-F4, 13985A-F7, 13985A-H9
• Germline Transmission: Earliest citation of germline transmission: J:188991
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 1553bp between positions 26048043-26049595 of Chromosome 17 (Build GRCm39). (J:136110)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 1 line available
• Carrying any Jmjd8 Mutation: 19 strains or lines available

Notes

Cell line 13985A-A5 was not successfully used to make chimeric mice. Germline transmission was not accomplished. J:246535

References

• Original: J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008
• All: 3 reference(s)