Kif22tm1(KOMP)Mbp
Targeted Allele Detail
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Symbol: |
Kif22tm1(KOMP)Mbp |
Name: |
kinesin family member 22; targeted mutation 1, Mouse Biology Program, UC Davis |
MGI ID: |
MGI:4456564 |
Gene: |
Kif22 Location: Chr7:126626901-126641639 bp, - strand Genetic Position: Chr7, 69.29 cM
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IMPC: |
Kif22 gene page |
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Mutant Cell Lines: |
DEPD00504_2_A09, DEPD00504_2_A10, DEPD00504_2_A11, DEPD00504_2_B09, DEPD00504_2_B10, DEPD00504_2_B11, DEPD00504_2_B12, DEPD00504_2_C09, DEPD00504_2_C10, DEPD00504_2_C12, DEPD00504_2_D09, DEPD00504_2_D12, DEPD00504_2_E09, DEPD00504_2_E10, DEPD00504_2_E11, DEPD00504_2_E12, DEPD00504_2_F09, DEPD00504_2_F11, DEPD00504_2_F12, DEPD00504_2_G10, DEPD00504_2_G11, DEPD00504_2_H09, DEPD00504_2_H10, DEPD00504_2_H12 |
Germline Transmission: |
Unknown
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Parent Cell Line: |
JM8A3 (ES Cell)
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Strain of Origin: |
C57BL/6N-Atm1Brd
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Project Collection: |
KOMP-CSD
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Allele Type: |
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Targeted (Null/knockout, Reporter) |
Mutations: |
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Insertion, Intragenic deletion
Vector: L1L2_Bact_P
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Mutation details: The insertion of the L1L2_Bact_P cassette created a deletion of size 1633 starting at position 126632003 and ending at position 126633636 of Chromosome 7 (Genome Build GRCm39). This deletion results in the removal of functionally critical exon(s). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml
(J:157064)
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Original: |
J:157064 University of California, Davis, Alleles produced for the KOMP project by the University of California, Davis. MGI Direct Data Submission. 2010; |
All: |
1 reference(s) |
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