Mir451a^tm1.1Doca
Targeted Allele Detail

Summary

• Symbol: Mir451a^tm1.1Doca
• Name: microRNA 451a; targeted mutation 1.1, Donal O'Carroll
• MGI ID: MGI:4829619
• Gene: Mir451a Location: Chr11:77963996-77964067 bp, + strand Genetic Position: Chr11, 46.74 cM
• Alliance: Mir451a^tm1.1Doca page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:163418
• Parent Cell Line: IB10/E14IB10 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted between Mir144 and Mir451 and an FRT flanked neo cassette with a 5' loxP site. Flp mediated recombination removed the neo cassette leaving Mir451 floxed. (J:163418)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Mir451a Mutation: 4 strains or lines available

References

• Original: J:163418 Rasmussen KD, et al., The miR-144/451 locus is required for erythroid homeostasis. J Exp Med. 2010 Jul 5;207(7):1351-8
• All: 1 reference(s)