Cdk12^{tm1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Cdk12^{tm1(KOMP)Vlcg}
• Name: cyclin dependent kinase 12; targeted mutation 1, Velocigene
• MGI ID: MGI:4881317
• Gene: Cdk12 Location: Chr11:98093885-98169330 bp, + strand Genetic Position: Chr11, 61.75 cM, cytoband D
• Alliance: Cdk12^{tm1(KOMP)Vlcg} page
• IMPC: Cdk12 gene page

Mutation origin

• Mutant Cell Lines: 15634A-E5, 15634A-F2
• Germline Transmission: Earliest citation of germline transmission: J:204812
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 27710bp between positions 98094197-98121906 of Chromosome 11 (Build GRCm39). (J:136110)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 1 line available
• Carrying any Cdk12 Mutation: 75 strains or lines available

References

• Original: J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008
• All: 2 reference(s)