Eps15tm2e(KOMP)Wtsi
Targeted Allele Detail
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Symbol: |
Eps15tm2e(KOMP)Wtsi |
Name: |
epidermal growth factor receptor pathway substrate 15; targeted mutation 2e, Wellcome Trust Sanger Institute |
MGI ID: |
MGI:5002922 |
Gene: |
Eps15 Location: Chr4:109137465-109245014 bp, + strand Genetic Position: Chr4, 51.29 cM, cytoband C7
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IMPC: |
Eps15 gene page |
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Mutant Cell Lines: |
EPD0053_1_A08, EPD0053_1_B07, EPD0053_1_B09, EPD0053_1_C09, EPD0053_1_E08, EPD0053_1_G07, EPD0053_1_H07, EPD0053_1_H08, EPD0053_1_H09 |
Germline Transmission: |
Unknown
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Parent Cell Line: |
JM8.N4 (ES Cell)
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Strain of Origin: |
C57BL/6N
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Project Collection: |
KOMP-CSD
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Allele Type: |
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Targeted (Null/knockout, Reporter) |
Mutation: |
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Insertion
Vector: L1L2_gt0
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Mutation details: The L1L2_gt0 cassette was inserted at position 109178803 of Chromosome 4 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT flanked lacZ/neomycin sequence followed by a loxP site. Insertion of this cassette creates a reporter knockout mouse. Cre expression will remove the neomycin selection cassette. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml
(J:148605, J:173534)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Eps15 Mutation: |
66 strains or lines available
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Original: |
J:148605 Wellcome Trust Sanger Institute, Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2009; |
All: |
2 reference(s) |
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