Tg(Mpz*Ala221fs)4Msch
Transgene Detail
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Symbol: |
Tg(Mpz*Ala221fs)4Msch |
Name: |
transgene insertion 4, Melitta Schachner |
MGI ID: |
MGI:5003323 |
Synonyms: |
P0ins4, TgP0ins4, Tg(P0)ins4Msch |
Transgene: |
Tg(Mpz*Ala221fs)4Msch Location: unknown
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Alliance: |
Tg(Mpz*Ala221fs)4Msch page
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Transgene Type: |
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Transgenic (Inserted expressed sequence) |
Mutation: |
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Insertion
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Tg(Mpz*Ala221fs)4Msch expresses
1 gene
Transgene expresses:
Organism |
Expressed Gene |
Note |
mouse |
Mpz (MGI:103177) |
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Mutation details: The transgenic construct contains a mutant form of the mouse peripheral myelin protein zero (Mpz) gene in which a 97 bp fragment of a human MPZ cDNA, extending from the second nucleotide of exon 6 and encompassing the "P0ins" insertion associated with Dejerine-Sottas syndrome (DSS), has replaced the corresponding region of the mouse gene. The mutation comprises the insertion of CG between nucleotides 662 and 663, in exon 6, that causes a frameshift following amino acid 221 (Ala221fs).
(J:82809)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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Original: |
J:82809 European Mouse Mutant Archive, Information obtained from the European Mouse Mutant Archive (EMMA). Unpublished. 2003-2013; |
All: |
1 reference(s) |
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