Gjd4^tm1.1Malt
Targeted Allele Detail

Summary

• Symbol: Gjd4^tm1.1Malt
• Name: gap junction protein, delta 4; targeted mutation 1.1, Julia von Maltzahn
• MGI ID: MGI:5009133
• Gene: Gjd4 Location: Chr18:9278607-9282809 bp, - strand Genetic Position: Chr18, 4.91 cM
• Alliance: Gjd4^tm1.1Malt page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:172698
• Parent Cell Line: H1 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The coding region was replaced with an EGFP and FRT-flanked neo cassette. Flp-mediated recombination removed the neo cassette. Immunohistochemistry confirmed the absence of protein expression in intercostal muscles of E13.5 muscles. (J:172698)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gjd4 Mutation: 28 strains or lines available

References

• Original: J:172698 von Maltzahn J, et al., Connexin39 deficient mice display accelerated myogenesis and regeneration of skeletal muscle. Exp Cell Res. 2011 May 1;317(8):1169-78
• All: 1 reference(s)