Aurkbtm2.1Mama
Targeted Allele Detail
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Symbol: |
Aurkbtm2.1Mama |
Name: |
aurora kinase B; targeted mutation 2.1, Marcos Malumbres |
MGI ID: |
MGI:5056431 |
Synonyms: |
Aurkb(loxZ) |
Gene: |
Aurkb Location: Chr11:68936477-68942490 bp, + strand Genetic Position: Chr11, 42.32 cM
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Alliance: |
Aurkbtm2.1Mama page
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Germline Transmission: |
Earliest citation of germline transmission:
J:173575
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Conditional ready, No functional change) |
Mutation: |
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Insertion
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Mutation details: Exons 2 - 4 were flanked with wild-type and mutant loxP sites, an inverted IRES-lacZ cassette was inserted between exons 4 and 5 inside the loxP sites, and an FRT flanked neo cassette was inserted between exons 4 and 5 outside the loxP sites via homologous recombination. Flp mediated recombination removed the neo cassette.
(J:173575)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Aurkb Mutation: |
23 strains or lines available
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Original: |
J:173575 Fernandez-Miranda G, et al., Genetic disruption of aurora B uncovers an essential role for aurora C during early mammalian development. Development. 2011 Jul;138(13):2661-72 |
All: |
2 reference(s) |
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