Tg(H2-Kb-NFKB2*)808Hfdg
Transgene Detail
|
Symbol: |
Tg(H2-Kb-NFKB2*)808Hfdg |
Name: |
transgene insertion 808, Han-Fei Ding |
MGI ID: |
MGI:5141435 |
Synonyms: |
p80HT, p80HT_808 |
Transgene: |
Tg(H2-Kb-NFKB2*)808Hfdg Location: unknown
|
Alliance: |
Tg(H2-Kb-NFKB2*)808Hfdg page
|
|
Strain of Origin: |
(C57BL/6J x SJL/J)F2
|
|
Transgene Type: |
|
Transgenic (Humanized sequence, Inserted expressed sequence) |
Mutation: |
|
Insertion
|
|
|
Tg(H2-Kb-NFKB2*)808Hfdg expresses
1 gene
Transgene expresses:
Organism |
Expressed Gene |
Homolog in Mouse |
Note |
human |
NFKB2 (4791) |
|
|
|
|
|
Mutation details: The human p80HT coding sequence was amplified by PCR, using a human fetus Marathon-ready cDNA library (Clontech) as the template and specific primers based on the published p80HT sequence (GenBank U09609), and cloned into pHSE3', a vector containing an H-2Kb promoter and an immunoglobulin mu chain enhancer for transgene expression in lymphocytes. Line 808 was generated.
(J:123872)
|
|
|
Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
|
|
Original: |
J:123872 Zhang B, et al., NF-kappaB2 mutation targets TRAF1 to induce lymphomagenesis. Blood. 2007 Jul 15;110(2):743-51 |
All: |
1 reference(s) |
|