Malat1^{Gt(IST14461G11)Tigm}
Gene trapped Allele Detail

Summary

• Symbol: Malat1^{Gt(IST14461G11)Tigm}
• Name: metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA); gene trap IST14461G11, Texas A&M Institute for Genomic Medicine
• MGI ID: MGI:5231311
• Synonyms: Malat-1 KO
• Gene: Malat1 Location: Chr19:5845718-5852700 bp, - strand Genetic Position: Chr19, 4.34 cM
• Alliance: Malat1^{Gt(IST14461G11)Tigm} page

Mutation origin

• Mutant Cell Line: IST14461G11
• Germline Transmission: Earliest citation of germline transmission: J:257182
• Parent Cell Line: Lex3.13 (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Gene trapped
• Mutation: Insertion of gene trap vector
• Mutation details: A retroviral insertion disrupted the gene. Ablation of expressed transcript in homozygous mice was confirmed by RT-PCR. (J:257182)
• Sequence Tags: Sequence tag details (2 tags)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  IST14461G11HMR1	JM322291 ; (MGI Seq Detail)	inverse PCR	Chr19:5852228-5852449 bp (-)
  IST14461G11BBF1	JM322290 ; (MGI Seq Detail)	inverse PCR	Chr19:5852447-5852506 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  11 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 1 line available
• Carrying any Malat1 Mutation: 9 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 7 reference(s)