Gt(ROSA)26Sor^{tm1(ACTB-cre,-EGFP)Ics}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1(ACTB-cre,-EGFP)Ics}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Mouse Clinical Institute
• MGI ID: MGI:5285392
• Synonyms: ROSA26Cre-GFP, Rosa26^{tm1(AC.cre2AeGFP)Ics}, Rosa^Cre-GFP
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1(ACTB-cre,-EGFP)Ics} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:185484
• Parent Cell Line: BD10 (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Recombinase, Reporter)
• Mutation: Insertion
• Gt(ROSA)26Sor^{tm1(ACTB-cre,-EGFP)Ics} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	ACTB

• Mutation details: A construct, which contains a beta actin promoter driving ubiquitous expression of cre and EGFP separated by a 2a peptide sequence, was inserted into the locus. (J:185484)

Generation of the Gt(ROSA)26Sor^{tm1(ACTB-cre,-EGFP)Ics} allele

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	ACTB (species not specified) Summary of all recombinase alleles driven by ACTB.

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 992 strains or lines available

References

• Original: J:185484 Birling MC, et al., Highly-efficient, fluorescent, locus directed cre and FlpO deleter mice on a pure C57BL/6N genetic background. Genesis. 2012 Jun;50(6):482-9
• All: 24 reference(s)