Gt(ROSA)26Sor^tm3(CFP)Mgn
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^tm3(CFP)Mgn
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 3, Mark A Magnuson
• MGI ID: MGI:5287869
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^tm3(CFP)Mgn page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:174255
• Parent Cell Line: TL1/TL-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (RMCE-ready, Reporter)
• Mutation: Insertion
• Mutation details: Recombinase mediated cassette exchange (RMCE) replaced the selection cassettes in Gt(ROSA)26Sor^tm1Mgn with the 5'UTR Xenopus beta-globin translation enchancer, cyan fluorescent protein (CFP), beta-globin intron, polyadenylation sequence, and an FRT-flanked neo cassette. (J:174255)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 993 strains or lines available

Notes

This allele was generate from Gt(ROSA)26Sor^tm1Mgn.

References

• Original: J:174255 Chen SX, et al., Quantification of factors influencing fluorescent protein expression using RMCE to generate an allelic series in the ROSA26 locus in mice. Dis Model Mech. 2011 Jul-Aug;4(4):537-47
• All: 1 reference(s)