Irf5^tm1Ppr
Targeted Allele Detail

Summary

• Symbol: Irf5^tm1Ppr
• Name: interferon regulatory factor 5; targeted mutation 1, Paula Pitha-Rowe
• MGI ID: MGI:5291913
• Gene: Irf5 Location: Chr6:29526624-29541870 bp, + strand Genetic Position: Chr6, 12.36 cM
• Alliance: Irf5^tm1Ppr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:176418
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• LoxP sites were inserted to flank exon 2, which encodes part of the DNA binding site. (J:176418)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Irf5 Mutation: 28 strains or lines available

References

• Original: J:176418 Pitha-Rowe P, Creation of a conditional targeted mutation in interferon regulatory factor 5 (Irf5). MGI Direct Data Submission. 2011
• All: 25 reference(s)